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Malabsorption issues due to gastrointestinal conditions

As people age, their ability to absorb B12 from food declines due to atrophic gastritis, which reduces stomach acid production

Why B12 Injections Work Better Than Tablets for Some People When you take B12 as a tablet, it travels through your digestive system before reaching your bloodstream

It activates the MAPK/ERK signaling pathway, which tells fibroblasts (the cells that produce collagen) to ramp up production

High-dose methionine supplementation has theoretical concerns regarding homocysteine elevation, though this is unlikely at typical lipotropic injection doses